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| Stemolecule™ (-)-Indolactam V |
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| Description |
| Stemolecule™ (-)-Indolactam V is an activator of protein kinase C (PKC) isozymes (alpha, beta-I, beta-II, gamma, delta, epsilon, eta, theta)1. PKC isozymes play a crucial role in cellular signal transduction via the second messenger, 1,2-diacyl-sn-glycerol (DG)1. Indolactam was identified in a high-content chemical screen as a small molecule inducer of human embryonic stem cell differentiation to functional insulin-secreting beta cells at the definitive endoderm cell stage thereby increasing the number of Pdx1-expressing pancreatic progenitor cells2. |
| Disclaimer |
| This Stemgent® Product is exclusively distributed by Miltenyi Biotec outside the USA and Israel. |
| Specifications and technical documents |
| Specification SheetsMaterial Safety Data Sheets
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| Figure 1 |
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| Details |
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| Products |
| Stemolecule (-)-Indolactam V |
- 300 µg
- Stemgent Catalog # 04-0020
130-095-570
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| References |
| 1. Irie et al. (2004) Curr Pharm Des 10: 1371–1385. |
| 2. Chen et al. (2009) Nat Chem Biol 5: 258–265. |
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