|
|
 |
|
| Description |
| The aminopyrimidine CHIR99021 is the most selective inhibitor of glycogen synthase kinase 3β (GSK3β) reported to date1, 2. Unlike alsterpaullone, kenpaullone, SB214763, and SB415286 that are potent inhibitors of GSK-3, CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) with 350-fold selectivity toward GSK-3β compared to CDKs with a Ki of <10 nM in vitro3. |
| Disclaimer |
| This Stemgent® Product is exclusively distributed by Miltenyi Biotec outside the USA and Israel. |
| Specifications and technical documents |
| Specification SheetsMaterial Safety Data Sheets
|
| |
|
| Figure 1 |
 |
|
| Figure 2 |
 |
|
| Figure 3 |
| Stemolecule™ CHIR99021 chemical structure. |
 |
|
|
|
|
| Favorites / Prices |
Request prices or add products to your favorite list.
|
| Details |
|
| Products |
| Stemolecule CHIR99021 |
- 2 mg
- Stemgent Catalog # 04-0004
130-095-555
|
|
| References |
| 1. Ring et al. (2003) Diabetes 52: 588–595. |
| 2. Hall et al. (2000) J. Biol. Chem 275: 30169–30175. |
| 3. Finlay et al. (2004) BMC Molecular Biology 5: 15. |
|
| MACS Stem Cell newsletter |
|
Stay current with important developments in stem cell research by subscribing to
Stem Cell Updates.
|
|
© 1999 - 2012 Miltenyi Biotec ¦ Terms & conditions ¦ Legal notes
|
