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| Overview |
| Clone AC128 recognizes the CD31 antigen, also known as platelet endothelial cell adhesion molecule 1 (PECAM-1) or ENDO-CAM and can be used to identify and enumerate human or non-human primate CD31+ cells by flow cytometry or fluorescence microscopy. |
| Details |
Background information
CD31, a 120–140 kDa single-chain transmembrane glycoprotein, is present on virtually all monocytes, platelets, and granulocytes. CD31 is also expressed by lymphocyte subsets. During maturation of CD4+ T cells, the expression of CD31 changes: CD4+ recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells.1 CD31 is highly expressed on endothelial cells, especially at their juncture, and is also known ENDO-CAM. |
| Cross-reactivity |
This monoclonal antibody was tested to cross-react with - Rhesus monkey (Macaca mulatta)
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| Clone | Isotype |
| AC128 | Mouse IgG1 |
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| Figure 1 |
| Human PBMCs were stained with CD31-FITC (A), CD31-PE (B) or CD31-APC (C) and CD4. Cells were analyzed by flow cytometry. |
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| Figure 2 |
| Rhesus monkey PBMCs were stained with CD31-APC and CD4-FITC and analyzed by flow cytometry. |
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| Favorites / Prices |
Request prices or add products to your favorite list.
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| Details |
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| Products |
| CD31-FITC, human |
- for 100 tests (1)
Download datasheet
130-092-654
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| CD31-PE, human |
- for 100 tests (1)
Download datasheet
130-092-653
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| CD31-APC, human |
- for 100 tests (1)
Download datasheet
130-092-652
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 μL. |
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| References |
| 1. Kimmig et al. (2002) J. Exp. Med. 195: 789–794. |
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