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| Stemgent® Purified Mouse anti-Mouse/Human βIII Tubulin Antibody |
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| Description |
| The Stemgent® Purified Mouse anti-Mouse/Human βIII-Tubulin Antibody was screened on neural cells derived from mouse and human ES cells via directed differentiation and selected as the best application-tested antibody for βIII-tubulin. This antibody was generated against the peptide (ESESQGPK) derived from the C-terminus of the human βIII-tubulin protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of α and β subunits. βIII-tubulin is regarded as a specific probe for the cells of neuronal origin as well as for tumors originating from these cells. The expression of βIII tubulin has been suggested to be one of the earliest markers to signal neuronal commitment in primitive neuroepithelium1-8. |
| Clone | Isotype |
| TU-20 | Mouse IgG1 |
| Specifications and technical documents |
| Specification SheetsMaterial Safety Data SheetsProtocols
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| Figure 1 |
| Directed differentiation of mouse embryonic stem cells (R1) towards the neural lineage. |
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| Figure 2 |
| Directed differentiation of human embryonic stem cells (H9) towards the neural lineage. |
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| Details |
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| Products |
| Stemgent® Purified Mouse anti-Mouse/Human βIII Tubulin Antibody |
- 50 µg - Stemgent Catalog #09-0076 130-095-674
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| References |
| 1. Draberova et al. (1998) Histochem Cell Biol 109: 231-239 |
| 2. Peknicova et al. (2001) Biol Reprod 65: 672-679 |
| 3. Jirásek et al. (2009) Indian J Med Res 129: 89-94 |
| 4. Kukharsky et al. (2004) Exp Cell Res 298: 218-228 |
| 5. Jirasek et al. (2007) Folia Histochem Cytobiol 45: 41-45 |
| 6. Katsetos et al. (2007) Neurochem Res 32: 1387-1398 |
| 7. Theodorou et al. (2009) Genes Dev 23: 575-88 |
| 8. Caccamo et al. (1989) Lab Invest 60: 390-398 |
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