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| Stemgent® Phycoerythrin (PE) anti-Human TRA-1-60 Antibody |
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| Description |
| The TRA-1-60 monoclonal antibody reacts with a pluripotent stem cell-specific antigen expressed on undifferentiated human embryonic stem (ES) cells, embryonal carcinoma (EC) cells, and embryonic germ (EG) cells. The expression of TRA-1-60 on human ES cells is down-regulated upon differentiation. The TRA-1-60 antibody recognizes a neuraminidase-resistant carbohydrate epitope expressed on podocalyxin, a member of the CD34-related family of sialomucins. Podocalyxin is a transmembrane glycoprotein, which has been implicated in the development of aggressiveness in a variety of cancers, including breast and prostate cancer. |
| Clone | Isotype |
| TRA-1-60 | Mouse IgMκ |
| Specifications and technical documents |
| Specification SheetsMaterial Safety Data SheetsProtocols
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| Figure 1 |
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| Details |
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| Products |
| Stemgent Phycoerythrin (PE) anti-Human TRA-1-60 Antibody |
- 1 mL
- Stemgent Catalog #09-0009
130-095-624
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| References |
| 1. Takahashi et al. (2007) Cell 131: 861–872. |
| 2. Yu et al. (2007) Science 318: 1917-1920. |
| 3. Schopperle and DeWolf (2007) Stem Cells 25: 723–730. |
| 4. Chin et al. (2007) J Biotechnol. 130: 320–328. |
| 5. Badcock et al. (1999) Cancer Res. 59: 4715–4719. |
| 6. Andrews et al. (1984) Hybridoma 3: 347-361. |
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