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| GadoSpin™ P, MRI contrast agent |
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| Description |
GadoSpin P is a polymeric gadolinium-based contrast agent of high molecular weight specifically formulated for pre-clinical magnetic resonance imaging (MRI).
It is a contrast agent of high relaxivity increasing the signal intensity in T1-weighted MRI due to a shortening of the spin-lattice relaxation time (T1).
Upon intravenous injection, GadoSpin P remains within the vascular system. Significant extravasation can be observed in fenestrated blood vessels of inflamed tissue or tumors.
GadoSpin P is mainly excreted via glomerular filtration (kidneys). |
| Applications |
GadoSpin P is indicated for use in MRI of small animals, for example mice, to facilitate the visualization of the vasculature.
Examples include contrast-enhanced magnetic resonance angiography (MRA), tumor characterization and therapy monitoring. |
| Disclaimer |
For laboratory and animal research use only.
Warning: Not for human or animal therapeutic or diagnostic use.
Make sure to comply with all laws and regulations governing research on animals. |
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| Schematic diagram of GadoSpin P. |
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| Details |
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| Products |
| GadoSpin P |
- 5 injections (1)
Components
- 1 vial
Download datasheet
130-095-136
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- 25 injections (1)
Components
- 5 vials
Download datasheet
130-095-137
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| (1) After reconstitution one vial contains 850 μL of imaging agent, sufficient for 5 injections of the recommended volume of 100 μL (for a 20–30 g mouse). |
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| References |
| 1. Franke, D. et al. (2010) In preparation. |
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