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| Overview |
| Mo-DC Maturation Medium is designed for the production of mature monocyte-derived dendritic cells (Mo-DCs) from immature Mo-DCs. |
| Details |
Large numbers of monocyte‑derived dendritic cells (Mo-DCs) can be generated ex vivo from purified CD14+ monocytes.1–6 The Mo-DC Maturation Medium is used for the maturation of immature Mo-DCs. Immature (Mo-DCs) can be easily obtained through differentiation of monocytes with a lot-to-lot consistent, standardized protocol using the Mo-DC Differentiation Medium.
The Mo-DC Maturation Medium is based on RPMI 1640 medium and contains L-glutamine and tumor necrosis factor alpha. It is also a component of the Mo-DC Generation Toolbox I and the Mo-DC Generation Toolbox II. |
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| Details |
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| References |
| 1. Banchereau, J. and Steinman, R. M. (1998) Nature 392: 245–252. |
| 2. Sallusto, F. and Lanzavecchia, A. (1994) J. Exp. Med. 179: 1109–1118. |
| 3. Dauer, M. et al. (2003) J. Immunol. 170: 4069–4076. |
| 4. Zhang, R. et al. (2006) Eur. J. Immunol. 36: 2993–3006. |
| 5. Sanarico, N. et al. (2006) J. Leukoc. Biol. 80: 555–562. |
| 6. Assier, E. et al. (2007) J. Leukoc. Biol. 81: 221–228. |
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