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| ExiTron™ nano 12000, CT contrast agent |
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| Description |
ExiTron nano 12000 is an alkaline earth metal-based nanoparticulate contrast agent specifically formulated for preclinical computed tomography (CT). It shows strong X-ray absorption due to the high metal load of the particles. Upon intravenous injection, ExiTron nano 12000 circulates in the blood stream for a prolonged time. It accumulates in the liver and spleen due to uptake by Kupffer cells (macrophages of the liver). |
| Applications |
ExiTron nano 12000 is indicated for use in CT of small animals, for example mice, to facilitate the visualization of the vasculature. Examples include contrast-enhanced angiography. |
| Disclaimer |
For laboratory and animal research use only. Warning: Not for human or animal therapeutic or diagnostic use. Make sure to comply with all laws and regulations governing research on animals. |
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| Figure 1 |
| Schematic diagram of an ExiTron nano 12000 nanoparticle. |
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| Details |
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| Products |
| ExiTron nano 12000 |
- 5 injections (1) Components - 1 vial Download datasheet 130-095-698
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- 25 injections (1) Components - 5 vials Download datasheet 130-095-700
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| (1) One vial contains 850 μL of imaging agent, sufficient for 5 injections of the recommended volume of 100 μL (for a 20–30 g mouse). |
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| References |
| 1. Boll, H. et al. (2010) J. Comput. Assist. Tomogr. 34: 783-790. |
| 2. Boll, H. et al. (2011) PLoS One 6: e25692. |
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