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| ExiTron™ nano 6000, CT contrast agent |
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| Description |
ExiTron nano 6000 is an alkaline earth metal-based nanoparticulate contrast agent specifically formulated for preclinical computed tomography (CT). It shows strong X-ray absorption due to the high metal load of theparticles. Upon intravenous injection, ExiTron nano 6000 circulates in the blood stream and is taken up by the Kupffer cells (macrophages of the liver). It accumulates particularly in the liver and spleen and provides long-term X-ray contrast. |
| Applications |
ExiTron nano 6000 is indicated for use in CT of small animals, for example mice, to facilitate the visualization of the liver and spleen. Examples include imaging of liver tumors and metastases. |
| Disclaimer |
For laboratory and animal research use only. Warning: Not for human or animal therapeutic or diagnostic use. Make sure to comply with all laws and regulations governing research on animals. |
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| Figure 1 |
| Schematic diagram of an ExiTron™ nano 6000 nanoparticle. |
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| Details |
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| Products |
| ExiTron nano 6000 |
- 5 injections (1) Components - 1 vial Download datasheet 130-095-146
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- 25 injections (1) Components - 5 vials Download datasheet 130-095-147
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| (1) One vial contains 850 μL of imaging agent, sufficient for 5 injections of the recommended volume of 100 μL (for a 20–30 g mouse). |
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| References |
| 1. Boll, H. et al. (2010) J. Comput. Assist. Tomogr. 34: 783-790. |
| 2. Boll, H. et al. (2011) PLoS One 6: e25692. |
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