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| Anti-Microfold (M) Cells – functional grade |
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| Overview |
| The pure – functional grade antibody is suited for functional assays, for example, antibody-mediated vaccination studies.1 The antibody is free of azide and preservatives. Endotoxin level is <0.01 ng/µg of protein as tested by LAL assay. |
| Details |
Background information
Microfold cells or membranous cells (M cells) have a high transcytotic activity and play an important role in the uptake of luminal antigens for induction of antigen-specific immune responses. This antibody (clone NKM 16-2-4) specifically binds to all subsets of M cells, but not epithelial cells or goblet cells located in Peyer's patches, nasopharynx-associated lymphoid tissue, and the intestinal villi in the gastrointestinal or respiratory tracts. |
| Clone | Isotype |
| NKM 16-2-4 | Rat IgG2c |
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| Favorites / Prices |
Request prices or add products to your favorite list.
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| Details |
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| Products |
| Anti-Microfold (M) Cells pure – functional grade, mouse |
- 500 µg in 500 µL
Download datasheet
130-096-150
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| References |
| 1. Nochi, T. et al. (2007) J. Exp. Med. 204: 2789–2796. |
| 2. Terahara, K. et al. (2008) J. Immunol. 180: 7840–846. |
| 3. Kim, S-H. et al. (2010) J. Immunol. 185: 5787–5795. |
| 4. Kim, D-Y. et al. (2011) J. Immunol. 186: 4253–426. |
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