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| Anti-DO11.10 TCR – functional grade |
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| Overview |
The antibody reacts with the T cell receptor (TCR) of the DO11.10 transgenic mouse and the TCR of the BALB/c-derived DO11.10 and DO11.10.24 T cell hybridoma. It is useful for, e.g., blocking of the antigen responses of the DO11.10 T cell hybridoma in vitro.
The antibody is free of azide and preservatives. Endotoxin level is <0.01 ng/µg of protein as tested by LAL assay. |
| Details |
Background information
The DO11.10 mouse model is a valuable tool for studies of T cell immigration, immunoregulation, development, activation, and function.
The KJ1-26 monoclonal antibody reacts with the T cell receptor (TCR) expressed on lymphocytes of the DO11.10 transgenic mouse and the TCR of the BALB/c-derived DO11.10 and DO11.10.24 T cell hybridoma. The DO11.10 TCR is specific for the chicken ovalbumin (OVA) peptide (323-339) in the context of I-A[d] major histocompatibility (MHC) molecules. Transgenic DO11.10 T cells also recognize OVA peptide from jungle fowl and turkey in the presence of A20-1.11, the H-2d-bearing, antigen-presenting B cell lymphoma. |
| Clone | Isotype |
| KJ1-26 | Mouse IgG2a |
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| Details |
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| Products |
| Anti-DO11.10 TCR pure – functional grade, mouse |
- 1 mg in 0.5 mL
Download datasheet
130-095-379
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