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| Anti-IL-13 – functional grade |
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| Overview |
| This antibody is suited for in vitro functional assays, e.g. neutralization of IL-13 activity. |
| Details |
Background information
Interleukin-13 (IL-13) is produced primarily by activated Th2 cells, but also by mast cells, NK cells, and dendritic cells. IL-13 exerts anti-inflammatory effects on monocytes and macrophages. Furthermore, it inhibits the expression of pro-inflammatory cytokines, such as IL-1β, TNF-α, IL-6, and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in an increased production of IgE. IL-13, in contrast to IL-4, fails to induce Th2 cell differentiation, one of the hallmarks of the allergic response. |
| Cross-reactivity |
This antibody has been tested to cross-react with
- Rhesus monkey (Macaca mulatta)
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| Clone | Isotype |
| JES10-5A2.2 | Rat IgG1 |
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| Favorites / Prices |
Request prices or add products to your favorite list.
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| Details |
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| Products |
| Anti-IL-13 pure – functional grade, human |
- 500 µg in 0.5 mL
Download datasheet
130-096-210
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