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| Anti-IL-12 (p40/p70) – functional grade |
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| Overview |
| This antibody is suited for in vitro functional assays, e.g. neutralization of IL-12 activity. The antibody is free of azide and preservatives. Endotoxin level is <0.01 ng/µg of protein as tested by LAL assay. |
| Details |
Background information
Interleukin 12 (IL-12) is a 70-75 kDa heterodimeric cytokine composed of a 40 kDa heavy chain and a 35 kDa light chain. It is produced mainly by monocytes/macrophages and dendritic cells, primarily in response to stimulation with bacterial or viral antigens. IL-12 displays various effects on both T and NK cells, playing an essential role in the interaction between innate and adaptive immunity.
Clone 8.6 reacts with both, the p40 chain and the p70 heterodimer of human IL-12. |
| Clone | Isotype |
| C8.6 | Mouse IgG1 |
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| Details |
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| Products |
| Anti-IL-12 (p40/p70) pure – functional grade, human |
- 500 μg in 0,5 mL
Download datasheet
130-095-755
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