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| Anti-iNKT – functional grade |
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| Overview |
The Anti-iNKT antibody, clone 6B11, reacts with the T cell receptor (TCR) Vα24-Jα18 on human and non-human primate invariant natural killer T cells (iNKT cells) and is useful for, e.g., specific activation and expansion of iNKT cells.1
The antibody is free of azide and preservatives. Endotoxin level is <0.01 ng/µg of protein as tested by LAL assay. |
| Details |
Background information
NKT cells represent a distinct lymphocyte population that co-expresses T cell and NK cell surface markers. A subset of human NKT cells, referred to as iNKT cells, expresses an invariant TCR α-chain with certain TCR β-chains (Vα24- Jα18 combined with Vβ11). The iNKT cells are implicated in immunoregulatory processes such as tolerance, host defense, and tumor surveillance.1,2 |
| Cross-reactivity |
This antibody was tested to cross-react with
- Rhesus monkey (Macaca mulatta)
- Cynomolgus monkey (Macaca fascicularis)
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| Clone | Isotype |
| 6B11 | mouse IgG1 |
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| Favorites / Prices |
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| Details |
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| Products |
| Anti-iNKT pure – functional grade, human |
- 100 µg in 1 mL
Download datasheet
130-094-865
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| References |
| 1. Exley, M. et al. (2008) Eur. J. Immunol. 38: 1756–1766. |
| 2. Montoya, J.C. et al. (2007) Immunology 122: 1–14. |
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