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| Overview |
| BAFF stands for B cell activating factor, also termed BLys. Human BAFF is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays. |
| Details |
Background information
BAFF is a ligand belonging to the TNF superfamily. BAFF is a critical survival and maturation factor for peripheral B cells. BAFF binds three receptors, TACI, BCMA, and the BAFF specific receptor BAFF-R, which is essential for the B cell promoting activity.
Human BAFF is a soluble 17.0 kDa protein composed of 153 amino acid residues that comprises the TNF-like portion of the extracellular domain of BAFF.
Quality description
Research-grade cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/µg (<1 EU/µg), and purities are >95%. The biological activity is tested in appropriate bioassays. |
| Alternative names |
| TNFSF13B |
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