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| PepTivator® MBP Isoform 1 – research grade |
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| Description |
PepTivator® MBP Isoform 1 is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the complete sequence of human myelin basic protein (MBP) isoform 1.
In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells. |
| Details |
Background information
Autoreactive T cells specific for myelin antigens, such as MBP, are considered to be involved in the pathogenesis of multiple sclerosis. MBP isoform 1, also known as Golli-MBP1, includes the amino acid sequence of the classic MBP isoform 5.
Downstream applications
PepTivator MBP Isoform 1 – research grade has been specifically developed for efficient in vitro stimulation of MBP isoform 1–specific T cells. Peptides of 15 amino acids in length and 11 amino acids overlap represent an optimized solution for stimulating both CD4+ and CD8+ T cells in various applications, including:
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| Details |
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| Products |
| PepTivator MBP Isoform 1 – research grade, human |
- 6 nmol/peptide for stimulation of 108 cells
Download datasheet
130-096-763
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