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| PepTivator® JCV VP1 - research grade |
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| Description |
PepTivator® JCV VP1 is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the complete sequence of the human JC virus (JCV) VP1 protein.
In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells. |
| Details |
Background information
JCV is a widespread human polyomavirus. Primary infection results in asymptomatic latent persistence of the virus. Immunodeficiency or immunosuppression allows virus reactivation. VP1 is the major capsid protein expressed late in the lytic cycle.
Downstream applications
PepTivator JCV VP1 - research grade has been specifically developed for the efficient in vitro stimulation of JCV VP1–specific T cells. Peptides of 15 amino acids in length and 11 amino acids overlap represent an optimized solution for stimulating both CD4+ and CD8+ T cells in various applications, including:
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| Details |
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| Products |
| PepTivator JCV VP1 - research grade, human |
- 6 nmol/peptide for stimulation of 108 cells
Download datasheet
130-096-502
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