| Description |
| CD105 MicroBeads are developed for the isolation of endothelial cells from single-cell suspensions of endothelial tissues, as well as for the isolation of marrow stromal cells (MSCs) from bone marrow aspirate.1,2 The CD105 antigen (endoglin) serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3, and is expressed on mature endothelial cells, on MSCs with mesodermal differentiation capacity, and on some leukemic cells of B lymphoid and myeloid origin. |
| Applications |
| CD105 MicroBeads can be used for the isolation of endothelial cells from single-cell suspensions of endothelial tissue, for example umbilical cord veins. They were also used for studies on mesengenesis and for in vitro investigations on hematological disorders.3 |
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| Figure 1 |
| Separation of CD105+ endothelial cells from a single-cell preparation of umbilical cord vein tissue using CD105 MicroBeads, an MS Column, and a MiniMACS™ Separator. |
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| Figure 2 |
| CD105+ cells isolated from umbilical cord vein endothelium. |
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