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| Overview |
| Anti-IgM MicroBeads were developed for the positive selection or depletion of cells expressing IgM on their surface from PBMCs or single-cell suspensions from lymphoid tissues. The Anti-IgM MicroBeads recognize human IgM antibodies. |
| Details |
Background information
IgM is the first immunoglobulin made by B cells in the immune response. Surface IgM is expressed on immature and mature B cells, while IgM heavy chain is expressed intracellularly in pre-B cells. |
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| Figure 1 |
| IgM+ cells were separated from human PBMCs using Anti-IgM MicroBeads, an MS Column, and a MiniMACS™ Separator. Cells were stained with Anti-IgM-APC and CD19-PE. |
| Before separation |
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| IgM+ cells |
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