CD45 MicroBeads
Description CD45 MicroBeads are designed for positive selection and depletion of leukocytes from peripheral blood, erythrocyte and thrombocyte preparations, lymphoid tissues, tumor tissues, as well as nonhematopoietic tissues. The CD45 antigen is expressed on all cells of hematopoietic origin except erythrocytes, platelets, and their precursor cells. Applications CD45 MicroBeads have been used to enrich fetal erythroblasts from maternal blood. They were also used to enrich epithelial tumor cells from peripheral blood, bone marrow, or lymphoid tissue by depletion of CD45+ leukocytes1 (for further information, click here). Pluripotent stem cells from human bone marrow have been enriched by depletion of cells labeled with CD235a (Glycophorin A) MicroBeads and CD45 MicroBeads.2 Columns For positive selection: MS, LS, XS or autoMACS™ Columns. For depletion: LD, CS, D, or autoMACS Columns.		Figure 1 Separation of human leukocyte-enriched buffy coat using CD45 MicroBeads, an MS Column, and a MiniMACS™ Separator. Cells are stained with CD45-FITC. Peripheral blood before separation CD45– cells CD45+ cells