|
|
 |
|
| Description |
The CD28 antibody recognizes the human CD28 antigen, a type I transmembrane protein, which is highly expressed on CD3+ thymocytes, most peripheral thymocytes and plasma cells. Binding of CD28 to its ligands CD80 or CD86 costimulates T cell effector function and T cell-dependent antibody production in vitro and in vivo. In the presence of antibodies directed against CD2 and CD3, CD28 antibodies stimulate T cell proliferation and cytokine production.
This antibody cross-reacts with rhesus monkey (Macaca mulatta) and cynomolgus monkey (Macaca fascicularis) cells. |
| Applications |
| The CD28 antibody can be used to identify and enumerate non-human primate CD28+ cells by flow cytometry or fluorescence microscopy. |
| Clone | Isotype |
| 15E8 | Mouse IgG1 |
| |
| Figure 1 |
| Rhesus monkey PBMCs were stained with CD28-PE and CD8-APC and analyzed by flow cytometry. |
 |
|
| Figure 2 |
| Cynomolgus monkey PBMCs were stained with CD28-APC and CD3-PE and analyzed by flow cytometry. |
 |
|
|
|
|
| My favorites |
| Your current favorite list is empty. |
| Products |
| CD28-PE, human |
- For 100 tests (1)
Download data sheet
130-092-921
|
| CD28-APC, human |
- For 100 tests (1)
Download data sheet
130-092-923
|
| CD28-Biotin, human |
- For 100 tests (2)
Download data sheet
130-092-955
|
| CD28-Biotin, human - functional grade |
- 100 µg in 1 mL
Download data sheet
130-093-386
|
| CD28 pure, human - functional grade |
- 100 µg in 1 mL
Download data sheet
130-093-375
|
| (1) One test corresponds to fluorescent labeling of up to 107 cell in a total volume of 100 µL. |
| (2) One test corresponds to labeling of up to 107 cell in a total volume of 100 µL. |
|
|