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| Description |
Killer immunoglobulin-like receptors (KIRs) are expressed on natural killer (NK) cells and subsets of CD8+ T cells and contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors with either 2 or 3 Ig-like extracellular domains (KIR2D or KIR3D, respectively). According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory and activating KIRs. The Anti-KIR2D antibody is a pan-KIR2D monoclonal antibody, recognizing all KIRs with two extracellular Ig-like domains, and recognizes both activating and inhibitory KIR isoforms (KIR2DS and KIR2DL, respectively).
This monoclonal antibody cross-reacts with rhesus monkey (Macaca mulatta) cells. |
| Applications |
| Identification and enumeration of KIR2D+ non-human primate cells by flow cytometry or fluorescence microscopy. |
| Clone | Isotype |
| NKVFS1 | Mouse IgG1 |
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| Figure 1 |
| Rhesus monkey PBMCs were stained with Anti-KIR2D-APC and CD16-PE and analyzed by flow cytometry. |
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| Products |
| Anti-KIR2D-PE, human |
- For 100 tests (1)
Download data sheet
130-092-688
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| Anti-KIR2D-APC, human |
- For 100 tests (1)
Download data sheet
130-092-687
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| Anti-KIR2D-Biotin, human |
- For 100 tests (2)
Download data sheet
130-092-904
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| Anti-KIR2D pure, human |
- 100 µg in 1 mL
Download data sheet
130-092-689
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µL. |
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