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| Description |
| Clone AF29-4D12 recognizes the human CD337 antigen, also known as NKp30, but also cross-reacts with rhesus monkey (Macaca mulatta) and cynomolgus monkey (Macaca fascicularis) NK cells, although expression levels seem to be lower than in human NK cells1. In humans, CD337 is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD337 is directly involved in target cell recognition and lysis and is expressed by all resting or activated NK cells and by a small subset of T cells. |
| Applications |
| The antibody can be used to identify and enumerate CD337 (NKp30)+ cells by flow cytometry or fluorescence microscopy. |
| Clone | Isotype |
| AF29-4D12 | Mouse IgG1 |
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| Figure 1 |
| Rhesus monkey (A) or cynomolgus monkey (B) PBLs were stained with CD337 (NKp30)-APC or -PE, respectively, and CD8-FITC. Cells were analyzed by flow cytometry. |
| A |
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| B |
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| Products |
| CD337 (NKp30)-PE, human |
- for 100 tests (1)
Download data sheet
130-092-483
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| CD337 (NKp30)-APC, human |
- for 100 tests (1)
Download data sheet
130-092-484
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| CD337 (NKp30)-Biotin, human |
- for 100 tests (2)
Download data sheet
130-092-553
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| CD337 (NKp30) pure, human |
- 100 µg in 1 mL
Download data sheet
130-092-554
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µL. |
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| References |
| 1. Mavilio et al. (2005) Blood 106: 1718–1725. |
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