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| Description |
| Clone FN50 is specific for human CD69 but cross-reacts with rhesus monkey (Macaca mulatta) and cynomolgus monkey (Macaca fascicularis) CD69, and is reported to crossreact with PBLs from baboon1. CD69 is involved in early events of lymphocyte, monocyte and platelet activation; cross-linking of CD69 induces the cytotoxic activity and costimulates cytokine production of activated NK cells and selected T cell clones. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. |
| Applications |
| The antibody can be used to identify and enumerate CD69+ cells by flow cytometry or fluorescence microscopy. The CD69 antibody is suitable for MACS® Control applications. |
| Clone | Isotype |
| FN50 | Mouse IgG1 |
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| Figure 1 |
| Rhesus monkey (A) or cynomolgus monkey (B) PBMCs were stimulated with Anti-Biotin MACSiBead™Particles loaded with CD2, CD3, and CD28 antibodies. Cells were stained with CD69-PE and CD4-APC and analyzed by flow cytometry. |
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| B |
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| Products |
| CD69-FITC, human |
for 100 tests (1)
Download data sheet
130-092-166
|
| CD69-PE, human |
for 100 tests (1)
Download data sheet
130-092-160
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| CD69-APC, human |
for 100 tests (1)
Download data sheet
130-092-159
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| CD69-Biotin, human |
for 100 tests (2)
Download data sheet
130-092-161
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µL. |
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| MACS References |
| 1. Guan-Xuan Lin et al. Leucocyte Typing VII, pp. 519–524. |
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