|
|
 |
|
| Description |
| Clone VEP13 is specific for human CD16 though also recognizes CD16 on rhesus monkey (Macaca mulatta) and cynomolgus monkey (Macaca fascicularis) cells. CD16 is a 50–80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form is found on human NK cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form is present on neutrophils. CD16 is expressed on the majority of rhesus monkey NK cells and on a subset of monocytes but not on granulocytes.The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone VEP13 recognizes both the extracellular domain of the transmembrane form as well as the GPI-linked form of the human CD16 antigen. |
| Applications |
| The CD16 antibody can be used to identify and enumerate CD16+ cells by flow cytometry or fluorescence microscopy. This antibody is suitable for MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. |
| Clone | Isotype |
| VEP13 | Mouse IgM |
| |
| Figure 1 |
| Rhesus monkey PBMCs were stained with CD16-PE and analyzed by flow cytometry. |
 |
|
| Figure 2 |
| Cynomolgus monkey PBMCs were stained with CD16-FITC and analyzed by flow cytometry. |
 |
|
|
|
|
| My favorites |
| Your current favorite list is empty. |
| Products |
| CD16-FITC, human |
for 100 tests (1)
Download data sheet
130-091-244
|
| CD16-PE, human |
for 100 tests (1)
Download data sheet
130-091-245
|
| CD16-APC, human |
for 100 tests (1)
Download data sheet
130-091-246
|
| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
|
|