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| Description |
| The human CD8 antibody cross-reacts with CD8 of rhesus monkey (Macaca mulatta)1 and cynomolgus monkey (Macaca fascicularis) cells. CD8 is expressed on rhesus monkey T cells and on a subset of rhesus monkey NK cells. CD8 is a disulfide-linked dimer, which exists either as a CD8α homodimer or as a CD8αβ heterodimer. It acts as a coreceptor of the T cell receptor and binds to the MHC Class I molecule. The CD8 antibody recognizes the α subunit of the antigen. |
| Applications |
| The CD8 antibody can be used to identify and enumerate cells by flow cytometry or fluorescence microscopy. This antibody is suitable for MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. |
| Clone | Isotype |
| BW135/80 | Mouse IgG2a |
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| Figure 1 |
| Rhesus monkey peripheral blood lymphocytes were stained with CD8-FITC and analyzed by flow cytometry. |
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| Figure 2 |
| Cynomolgus monkey PBMCs were stained with CD8-APC and analyzed by flow cytometry. |
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| References |
| 1. Jonker and Slingerland (1989) Leukocyte Typing IV (ed. W. Knapp et al.) pp. 1058–1063. |
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