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| Description |
| The CD28 antibody is specific for the mouse CD28 costimulatory molecule, expressed on most thymocytes, CD4+ and CD8+ T cells, and NK cells. Expression is down-regulated at late stages of terminal effector T cell differentiation. CD28 is a homodimeric type I transmembrane protein of the Ig receptor superfamily, composed of disulfide-linked 45 kDa subunits. Ligation of CD28 with CD80 (B7-1) and CD86 (B7-2) provides a costimulatory signal for T cell activation. |
| Applications |
| For the identification and enumeration of mouse CD28+ cells by fluorescence microscopy or flow cytometry. |
| Clone | Isotype |
| 37.51 | Hamster IgG2 |
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| Figure 1 |
| Mouse splenocytes were stained with CD28 antibodies conjugated to PE (a) or Biotin (b) and analyzed by flow cytometry. Cells stained with CD28-Biotin were stained with Anti-Biotin-PE in addition. All cells were stained with CD3ε-FITC. |
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| B |
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| Products |
| CD28-PE, mouse |
- for 100 tests (1)
Download data sheet
130-093-180
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| CD28-Biotin, mouse |
- for 100 tests (2)
Download data sheet
130-093-181
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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