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| Description |
| The Anti-Ly-6C antibody (clone 1G7.G10) specifically recognizes Ly-6C, a 14-17 kDa GPI-linked cell surface antigen that belongs to the Ly-6 family of murine surface glycoproteins. It is expressed on monocytes in the bone marrow and shortly after their migration into the circulation. Moreover, Ly-6C is expressed on memory T cells and CD11lowCD45R(B220)+ mPDCA1+ plasmacytoid DCs (pDCs) in different organs. In combination with Anti-mPDCA-1 antibodies, Ly-6C antibodies are a useful tool for the identification of mouse plasmacytoid dendritic cells (pDCs). |
| Applications |
| The antibody is suited for the identification and enumeration of Ly-6C on mouse cells by flow cytometry or fluorescence microscopy. |
| Clone | Isotype |
| 1G7.G10 | Rat IgG2a |
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| Figure 1 |
| Mouse splenocytes were stained with Anti-Ly-6C antibodies conjugated to FITC (A), PE (B), or APC (C), and analyzed by flow cytometry. Cells stained with Anti-Ly-6C-Biotin (D) were stained with Anti-Biotin-FITC. Additionally, cells were stained with Anti-mPDCA-1-APC or Anti-mPDCA-1-PE. |
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| B |
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| C |
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| D |
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| Products |
| Anti-Ly-6C-FITC, mouse |
- for 100 tests (1)
Download data sheet
130-093-134
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| Anti-Ly-6C-PE, mouse |
- for 100 tests (1)
Download data sheet
130-093-135
|
| Anti-Ly-6C-APC, mouse |
- for 100 tests (1)
Download data sheet
130-093-136
|
| Anti-Ly-6C-Biotin, mouse |
- for 100 tests (2)
Download data sheet
130-093-137
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µl. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µl. |
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