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| Description |
The CD16/32 antibody recognizes a shared epitope common to the CD16 and CD32 antigens. CD16 and CD32 are also known as FcyIII and FcyII, respectively, and bind to epitopes located in the constant region domain of IgG. CD16 and CD32 are expressed predominantly on cells of hematopoietic lineages, including B cells, monocytes, NK cells, granulocytess, and dendritic cells. They are also found on hematopoietic progenitor cells, where they appear to play a role in T and B cell development. Clone 93 monoclonal antibody blocks the binding of immunoglobulins to the Fc receptor. |
| Applications |
| Identification and enumeration of CD16/32+ mouse cells. Blocking of mouse Fc receptors. |
| Clone | Isotype |
| 93 | Rat IgG2a |
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| Figure 1 |
| Mouse splenocytes were stained with CD16/32 antibodies conjugated to PE (A), APC (B) or Biotin (C) and analyzed by flow cytometry. Cells stained with CD16/23-Biotin were stained with Anti-Biotin-PE in addition. |
| A |
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| B |
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| C |
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| Products |
| CD16/32-PE, mouse |
- for 100 tests (1) Download data sheet 130-092-572
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| CD16/32-APC, mouse |
- for 100 tests (1) Download data sheet 130-092-573
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| CD16/32-Biotin, mouse |
- for 100 tests (2) Download data sheet 130-092-570
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| CD16/32 pure, mouse |
- 100 µg in 1 mL Download data sheet 130-092-574
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100µl. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100µl. |
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