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| Description |
| Clone 6D5 recognizes the mouse CD19 antigen, a type I transmembrane glycoprotein expressed on B cells throughout their development from the early pro-B cell through the mature B cell stages. Its expression is down-regulated during terminal differentiation to plasma cells. CD19 associates with complement receptor CD21 and with CD81 on the cell surface of mature B cells, thereby forming a multi-molecular complex which signals synergistically to membrane IgM. CD19 is a critical regulator of B cell development, activation, and differentiation. It is also expressed on follicular dendritic cells and peritoneal mast cells. |
| Applications |
| The antibody can be used to identify and enumerate CD19+ cells by flow cytometry or fluorescence microscopy. The antibody is also suitable for MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. |
| Clone | Isotype |
| 6D5 | Rat IgG2a |
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| Figure 1 |
| Mouse splenocytes were stained with CD19 antibodies conjugated to FITC (A), PE (B), or APC (C) and analyzed by flow cytometry. |
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| B |
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| C |
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| Products |
| CD19-FITC, mouse |
- for 100 tests (1)
Download data sheet
130-092-042
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| CD19-PE, mouse |
- for 100 tests (1)
Download data sheet
130-092-041
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| CD19-APC, mouse |
- for 100 tests (1)
Download data sheet
130-092-039
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 μL. |
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