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| Description |
The Anti-IgG antibody detects all subclasses of human immunoglobulins of the IgG isotype. Clone IS11-3B2.2.3 recognizes the Fab region of IgG. IgG produced by B cells is the most abundant immunoglobulin in humans. It is expressed in a membrane-associated or a secreted form. Functions of IgGs include opsonization for phagocytosis, complement activation, feedback inhibition of B cell activation, and antibody-dependent cell-mediated cytotoxicity (ADCC). |
| Applications |
| Identification and enumeration of human IgG+ cells by flow cytometry or fluorescence microscopy. Intracellular staining of IgG-producing cells. |
| Clone | Isotype |
| IS11-3B2.2.3 | Mouse IgG1 |
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| Figure |
| Viable human leukocytes were stained with Anti-IgG antibodies conjugated to FITC (A), PE (B), APC (C), or Biotin (D) and with CD19 antibodies and analyzed by flow cytometry. Cells stained with Anti-IgG-Biotin were stained with Anti-Biotin-APC in addition. |
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| B |
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| C |
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| D |
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| Products |
| Anti-IgG-FITC, human |
- for 100 tests (1) Download data sheet 130-093-192
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| Anti-IgG-PE, human |
- for 100 tests (1) Download data sheet 130-093-193
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| Anti-IgG-APC, human |
- for 100 tests (1) Download data sheet 130-093-194
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| Anti-IgG-Biotin, human |
- for 100 tests (2) Download data sheet 130-093-195
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| Anti-IgG pure, human |
- 100 µg in 1 mL Download data sheet 130-093-197
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µL. |
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