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| Description |
Clone PJ2-22H3 detects the IgM isotype of human immunoglobulins. It reacts with the soluble as well as membrane-bound form of human IgM.
IgM is the first immunoglobulin produced by B cells in the immune response. Surface IgM is expressed on immature and mature B cells, whereas IgM heavy chain is expressed intracellularly in pre-B cells. IgM serves as the antigen receptor of naive B cells and is involved in B cell maturation and complement activation. |
| Applications |
| For the detection of human B cells expressing the IgM isotype of human immunoglobulins by fluorescence microscopy or flow cytometry. |
| Clone | Isotype |
| PJ2-22H3 | Mouse IgG1 |
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| Figure |
| Human PBMCs were stained with Anti-IgM antibodies conjugated to PE (A), APC (B), or Biotin (C) and analyzed by flow cytometry. Cells stained with Anti-IgM-Biotin were additionally stained with Anti-Biotin-PE. |
| A |
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| B |
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| C |
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| Products |
| Anti-IgM-PE, human |
for 100 tests (1)
Download data sheet
130-093-075
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| Anti-IgM-APC, human |
for 100 tests (1)
Download data sheet
130-093-076
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| Anti-IgM-Biotin, human |
for 100 tests (2)
Download data sheet
130-093-077
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| Anti-IgM pure, human |
100 µg in 1 mL
Download data sheet
130-093-078
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µL |
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