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| Description |
| The Anti-IgA2 antibody, clone IS11-21E11, detects the IgA2 subclass of human immunoglobulin. IgA1 is not detected. IgA is present either as monomer or in a secreted form as a multimer of 2-4 molecules, connected by the J-chain and the so-called secretory component. Secreted IgA is transported across epithelial cells and secreted into the lumen of the respiratory and gastrointestinal tract. IgA2 is produced by B cells in the mucosae and is the most abundant immunoglobulin in mucosal secretions. |
| Applications |
| Identification and enumeration of human IgA2+ cells by flow cytometry and fluorescence microscopy. Intracellular staining of IgA2-producing cells. |
| Clone | Isotype |
| IS11-21E11 | Mouse IgG1 |
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| Figure |
| Human PBMCs were stained with Anti-IgA2 antibodies conjugated to FITC (A), PE (B), APC (C), or Biotin (D) and with CD19 antibodies and analyzed by flow cytometry. Cells stained with Anti-IgA-Biotin were stained with Anti-Biotin-APC in addition. |
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| B |
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| C |
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| D |
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| Products |
| Anti-IgA2-FITC, human |
- for 100 tests (1) Download data sheet 130-093-069
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| Anti-IgA2-PE, human |
- for 100 tests (1) Download data sheet 130-093-070
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| Anti-IgA2-APC, human |
- for 100 tests (1) Download data sheet 130-093-079
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| Anti-IgA2-Biotin, human |
- for 100 tests (2) Download data sheet 130-093-080
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| Anti-IgA2 pure, human |
- 100 ÎĽg in 1 mL Download data sheet 130-093-081
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µL. |
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