Anti-IgA
Description The Anti-IgA antibody clone IS11-8E10 detects both subclasses of human IgA. IgA is present either as monomer or in a secreted form as a multimer of 2-4 molecules, connected by the J-chain and the so-called secretory component. Secreted IgA is transported across epithelial cells and secreted into the lumen of the respiratory and gastrointestinal tract. Applications Identification and enumeration of human IgA+ cells by flow cytometry and fluorescence microscopy. Intracellular staining of IgA-producing cells. Clone Isotype IS11-8E10 Mouse IgG1		Figure Human PBMCs were stained with Anti-IgA antibodies conjugated to FITC (A), PE (B), APC (C), or Biotin (D) and with CD19 antibodies and analyzed by flow cytometry. Cells stained with Anti-IgA-Biotin were stained with anti-Biotin-APC in addition. A B C D