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| Description |
Clone TB03 specifically recognizes human CD57. CD57, also known as HNK-1 or Leu-7, is an antigenic oligosaccharide moiety detected on extracellular proteins of certain cell types. In blood, CD57 is found on 15–20% of mononuclear cells, including subsets of NK and T cells, though not on erythrocytes, monocytes, granulocytes, or platelets. Also, CD57 expression can be found on a variety of neural cell types.
CD57 has been shown to be expressed on late stage effector CD8+ T cells. The frequency of CD57+ T lymphocytes is raised in a variety of diseases. CD57 expression is also increased on chronically activated CD8+ T cells in persistent viral infections, such as HIV. |
| Applications |
| Identification and enumeration of CD57+ cells by flow cytometry and fluorescence microscopy. The antibody is suitable for use in MACS® Control applications. For further information, please refer to the datasheet of the separation reagent. |
| Clone | Isotype |
| TB03 | Mouse IgM |
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| Figure 1 |
| Human PBMCs were stained with CD57 antibodies conjugated to FITC (A), PE (B), or APC (C) and analyzed by flow cytometry. Cells stained with CD57-Biotin were additionally stained with Anti-Biotin-PE (D). |
| A |
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| B |
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| C |
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| D |
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| Products |
| CD57-FITC, human |
- for 100 tests (1)
Download data sheet
130-092-174
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| CD57-PE, human |
- for 100 tests (1)
Download data sheet
130-092-139
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| CD57-APC, human |
- for 100 tests (1)
Download data sheet
130-092-141
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| CD57-Biotin, human |
- for 100 tests (2)
Download data sheet
130-092-620
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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