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| Description |
| The CD31 antibody recognizes the human CD31 antigen, a 120–140 kDa single-chain transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1). CD31 is present on virtually all monocytes, platelets, and granulocytes, and also on lymphocyte subsets. During maturation of CD4+ T cells, the expression pattern of CD31 changes: CD4+ recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells.1 CD31 is highly expressed on endothelial cells, especially at their juncture, and is also known ENDO-CAM. |
| Applications |
| The CD31 antibody can be used to identify and enumerate CD31+ cells by flow cytometry or fluorescence microscopy. This antibody is suitable for MACS® Control applications. For further details, please refer to the datasheet of the separation reagent. |
| Cross-reactivity |
- Rhesus monkey (Macaca mulatta)
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| Clone | Isotype |
| AC128 | Mouse IgG1 |
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| Figure 1 |
| Human PBMCs were stained with CD31-FITC (A), CD31-PE (B) or CD31-APC (C) and CD4. Cells were analyzed by flow cytometry. |
| A |
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| B |
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| C |
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| Products |
| CD31-FITC, human |
- For 100 tests (1)
Download data sheet
130-092-654
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| CD31-PE, human |
- For 100 tests (1)
Download data sheet
130-092-653
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| CD31-APC, human |
- For 100 tests (1)
Download data sheet
130-092-652
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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| MACS References |
| 1. Kimmig et al. (2002) J. Exp. Med. 195: 789–794.[1294] |
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