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| Description |
Immunoglobulins produced by B cells are composed of two heavy and two light chains, connected by disulfide bonds. Differences in the composition of the heavy chain constant regions determine the different isotypes. The light chains of all isotypes are either of κ or λ type.
Clone IS11-24D5 detects human Ig light chains of κ type. Heavy chains and light chains of the λ type are not detected. |
| Applications |
| Identification and enumeration of human immunoglobulins with κ light chains by flow cytometry or fluorescence microscopy. |
| Clone | Isotype |
| IS11-24D5 | Mouse IgG1 |
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| Figure 1 |
| Human PBMCs were stained with Anti-Igκ light chain antibodies coupled to FITC (a), PE (b) or APC (c) and analyzed by flow cytometry. Cells stained with Anti-Igκ Light Chain-Biotin were stained with Anti-Biotin-PE in addition (d). |
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| Figure 2 |
| Human PBMCs were fixed, permeabilized and intracellularly stained with Anti-Igκ Light Chain antibodies coupled to PE (a), or APC (b). Cells were analyzed by flow cytometry. |
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| Products |
| Anti-Ig κ Light Chain-FITC, human |
For 100 tests (1)
Download data sheet
130-093-053
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| Anti-Ig κ Light Chain-PE, human |
For 100 tests (1)
Download data sheet
130-093-054
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| Anti-Ig κ Light Chain-APC, human |
For 100 tests (1)
Download data sheet
130-093-043
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| Anti-Ig κ Light Chain-Biotin, human |
For 100 tests (2)
Download data sheet
130-093-042
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| Anti-Ig κ Light Chain pure, human |
100 µg in 1 mL
Download data sheet
130-093-041
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µL |
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