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CD161
Description
Clone 191B8 recognizes CD161, a C-type lectin membrane glycoprotein. CD161, also known as NKR-P1A, is expressed as an 80 kDa disulphide-linked homodimer and is found on most NK cells and subsets of T cells. In peripheral blood, CD161 is preferentially expressed on T cells of memory phenotype, but it can also be found on subsets of thymocytes and fetal liver T cells.
CD161 has been implicated in triggering NK-mediated cytotoxicity, contributing to target cell recognition by NK cells.
Applications
Detection and enumeration of CD161+ cells by flow cytometry or fluorescence microscopy.
Clone Isotype
191B8Mouse IgG2a
 
Figure 1
Human PBMCs were stained with CD161 antibodies conjugated to FITC (A), PE (B), APC (C) or Biotin (D). Cells stained with CD161-Biotin were additionally stained with Anti-Biotin-APC. Cells were analyzed by flow cytometry.
A
B
C
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Products
CD161-FITC, human
- For 100 tests (1)
Download data sheet
130-092-907
Qty:
 

CD161-PE, human
- For 100 tests (1)
Download data sheet
130-092-677
Qty:
 

CD161-APC, human
- For 100 tests (1)
Download data sheet
130-092-678
Qty:
 

CD161-Biotin, human
- For 100 tests (2)
Download data sheet
130-092-906
Qty:
 

CD161 pure, human
- 100 µg in 1 mL
Download data sheet
130-092-676
Qty:
 

(1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µl.
(2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µl.
Related products
NK cell separation reagents
CD56 Antibodies
Mouse IgG2a - isotype control antibodies
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