|
|
 |
|
| Description |
| Clone DX27 recognizes CD158b (KIR2DL2/DL3), a member of the killer immunoglobulin-like receptor (KIR) family expressed on CD56dimCD16+ natural killer (NK) cells and CD8+ T cells. KIRs contribute to the regulation of NK cell–mediated cytotoxicity and possess high allelic polymorphism with either 2 or 3 Ig-like extracellular domains (KIR2D or KIR3D). According to the length of their cytoplasmic tail, KIRs can be further subdivided in long-tailed inhibitory KIRs (KIR2DL or KIR3DL) and short-tailed activating KIRs (KIR2DS or KIR3DS). CD158b (KIR2DL2/DL3) acts as an inhibitory receptor and binds HLA-C (Cw1, Cw3, Cw7 and Cw8 supertypes). |
| Applications |
| The antibody is suitable for identification and enumeration of CD158b (KIR2DL2/DL3)+ cells by flow cytometry and fluorescence microscopy. |
| Clone | Isotype |
| DX27 | Mouse IgG2a |
| |
| Figure 1 |
| Human PBMCs were stained with CD158b (KIR2DL2/DL3)-PE (A) or -APC (B). |
| A |
 |
| B |
 |
|
|
|
|
| My favorites |
| Your current favorite list is empty. |
| Products |
| CD158b (KIR2DL2/DL3)-PE, human |
for 100 tests (1)
Download data sheet
130-092-618
|
| CD158b (KIR2DL2/DL3)-APC, human |
for 100 tests (1)
Download data sheet
130-092-617
|
| CD158b (KIR2DL2/DL3) pure, human |
100 µg in 1 mL
Download data sheet
130-092-615
|
| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL. |
|
|