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| Description |
| Clone FN50 recognizes the human CD69 antigen, also known as activation inducer molecule (AIM). CD69 is involved in the early events of lymphocyte, monocyte and platelet activation. Cross-linking of CD69 induces cytotoxic activity and costimulates cytokine production of activated NK cells and selected T cell clones. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. It is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. |
| Applications |
| The CD69 antibody can be used to identify and enumerate CD69+ cells by flow cytometry or fluorescence microscopy. It is suitable for studies of T cell activation and for analysis of cytokine expression in combination with cytokine secretion assays or intracellular cytokine staining. This antibody is suitable for MACS® Control applications. |
| Cross-reactivity |
- Rhesus monkey (Macaca mulatta)
- Cynomolgus monkey (Macaca fascicularis)
- Baboon
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| Clone | Isotype |
| FN50 | Mouse IgG1 |
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| Figure 1 |
| Human peripheral blood leukocytes were stained with CD69 antibodies conjugated to FITC (A), PE (B), APC (C) or Biotin (D). Cells were counterstained with CD4 antibodies and analyzed by flow cytometry. |
| A |
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| B |
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| C |
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| D |
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| Products |
| CD69-FITC, human |
- for 100 tests (1)
Download data sheet
130-092-166
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| CD69-PE, human |
- for 100 tests (1)
Download data sheet
130-092-160
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| CD69-APC, human |
- for 100 tests (1)
Download data sheet
130-092-159
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| CD69-Biotin, human |
- for 100 tests (2)
Download data sheet
130-092-161
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µL. |
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