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| Description |
| The CD71 antibody recognizes the transferrin receptor, which is essential for iron transport into proliferating cells. CD71 is expressed on marrow stromal cells (MSCs) from bone marrow1, on activated T and B lymphocytes, macrophages, and all proliferating cells. It is upregulated on lymphocytes during proliferative responses to antigens or mitogens but is not expressed on resting lymphocytes. CD71 is present on reticulocytes and erythroid progenitors in fetal liver, cord blood, and peripheral blood, yet it is lost as these differentiate to mature erythrocytes.2,3,4 |
| Applications |
| The CD71 antibody can be used to identify and enumerate CD71+ cells by flow cytometry or fluorescence microscopy. This antibody is suitable for MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. |
| Clone | Isotype |
| AC102 | Mouse IgG2a |
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| Figure 1 |
| Human cord blood mononuclear cells (CB-MNCs) were stained with CD71 antibodies conjugated to PE (A) or APC (B) and CD45-FITC and analyzed by flow cytometry. |
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| Products |
| CD71-PE, human |
for 100 tests (1)
Download data sheet
130-091-728
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| CD71-APC, human |
for 100 tests (1)
Download data sheet
130-091-727
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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| MACS References |
| 1. Pittenger et al. (1999) Science 284: 143–147.[3462] |
| 2. Judd et al. (1980) J. Exp. Med. 152: 1430–1435.[8311] |
| 3. Loken et al. (1987) Blood 69: 255–263.[8312] |
| 4. Phillips et al. (1984) J. Exp. Med. 159: 993–1008.[8313] |
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