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| Description |
| Clone AC104.3E3 recognizes the human CD33 antigen, a glycoprotein of 67 kDa belonging to the sialoadhesin superfamily. It also cross-reacts with rhesus monkey (Macaca mulata) and cynomolgus monkey (Macaca fascicularis) cells. The CD33 antigen is highly expressed on human monocytes but weakly on granulocytes and some — but not all — myeloid dendritic cells. The CD33 antigen is also found on myeloid progenitor cells (CFU-GEMM, CFU GM, CFU-G, BFU-E) but is not expressed on lymphocytes, platelets, erythrocytes, or primitive hematopoietic stem cells. |
| Applications |
| The CD33 antibody can be used to identify and enumerate CD33+ cells by flow cytometry or fluorescence microscopy. CD33-PE is suitable for MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. |
| Cross-reactivity |
- Rhesus monkey (Macaca mulatta)
- Cynomolgus monkey (Macaca fascicularis)
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| Clone | Isotype |
| AC104.3E3 | Mouse IgG1 |
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| Figure 1 |
| Human PBMCs were stained with CD33 antibodies conjugated to PE (A) or APC (B) and analyzed by flow cytometry. |
| A |
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| B |
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| Products |
| CD33-PE, human |
for 100 tests (1)
Download data sheet
130-091-732
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| CD33-APC, human |
for 100 tests (1)
Download data sheet
130-091-731
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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