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| Description |
| The CD19 antibody recognizes the human CD19 antigen, a type-I transmembrane glycoprotein of 95 kDa that belongs to the immunglobulin superfamily. CD19 is expressed on B cells throughout most stages of B cell differentiation, though its expression is down-regulated during their terminal differentiation to plasma cells. Expression of CD19 is also found in the majority of B cell–derived malignancies. CD19 is further present on follicular dendritic cells. On B cells, CD19 associates with CD21, CD81, and CD225 (Leu-13) forming a signal transduction complex. CD19 is a critical regulator in B cell development, activation, and differentiation. |
| Applications |
| The CD19 antibody can be used to identify and enumerate CD19+ cells by flow cytometry or fluorescence microscopy. This antibody is suitable for MACS® Control applications. For further details, please refer to the datasheet of the separation reagent. |
| Clone | Isotype |
| LT19 | Mouse IgG1 |
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| Figure 1 |
| Human PBMCs were stained with CD19-FITC (A), CD19-PE (B), and CD19-APC (C) and analyzed by flow cytometry. |
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| B |
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| C |
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| Products |
| CD19-FITC, human |
for 100 tests (1)
Download data sheet
130-091-328
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| CD19-PE, human |
for 100 tests (1)
Download data sheet
130-091-247
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| CD19-APC, human |
for 100 tests (1)
Download data sheet
130-091-248
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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