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| Description |
The CD61 antibody recognizes the human CD61 antigen which is also known as the integrin β3-subunit. CD61 associates with CD41 to form the heterodimeric gpIIb/gpIIIa
complex that is present on human megakaryocytes and platelets and mediates cell adhesion processes. Together with CD51, CD61 forms the vitronectin receptor, which is present on platelets as well as on a variety of other cell types such as osteoclasts and endothelial vessel cells. The CD61 antibody specifically recognizes the integrin β3-chain of both heterodimeric complexes. |
| Applications |
| The CD61 antibody can be used to identify and enumerate CD61+ cells by flow cytometry or fluorescence microscopy. This antibody is suitable for MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. |
| Cross-reactivity |
- Rhesus monkey (Macaca mulatta)
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| Clone | Isotype |
| Y2/51 | Mouse IgG1 |
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| Figure 1 |
| PBMCs were stained with CD61-PE and CD45-FITC and analyzed by flow cytometry. Platelets can be identified as CD61+CD45- cells. Note that a few cells appear to be CD45 and CD61 double positive. These are platelets interacting with leukocytes. |
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| Products |
| CD61-PE, human |
for 100 tests (1)
Download data sheet
130-081-501
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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