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| Description |
Clone AF12-7H3 recognizes the human CD56 antigen, a glycoprotein of the Ig-superfamily also known as neural cell adhesion molecule (NCAM) which is expressed in blood on practically all resting and activated NK cells and on a minor subset of CD3+ T cells.
CD56 is also expressed in brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal-derived tumors, myelomas, and myeloid leukemias also express CD56.
The monoclonal antibody AF12-7H3 recognizes an epitope distinct from those recognized by the CD56-specific mAbs NCAM16.2 and B159. |
| Applications |
| The CD56 antibody can be used to identify and enumerate CD56+ cells by flow cytometry or fluorescence microscopy. |
| Cross-reactivity |
- Rhesus monkey (Macaca mulatta)
- Cynomolgus monkey (Macaca fascicularis)
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| Clone | Isotype |
| AF12-7H3 | Mouse IgG1 |
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| Figure 1 |
| Human peripheral blood lymphocytes were stained with CD56-PE (A) or CD56-APC (B) and analyzed by flow cytometry. |
| A |
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| B |
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| Products |
| CD56-PE, human |
- for 100 tests (1)
Download data sheet
130-090-755
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| CD56-APC, human |
- for 100 tests (1)
Download data sheet
130-090-843
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| CD56 pure, human |
- 50 ÎĽg in 1 mL
Download data sheet
130-090-955
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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