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| Description |
The CD11b (Mac-1 α; integrin αM chain) antibody reacts with the 170 kDa αM-subunit of CD11b/CD18 heterodimer (Mac-1, αMß2 integrin). It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X.
The monoclonal CD11b antibody recognizes the human, mouse, and non-human primate CD11b antigen. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on NK cells and some activated lymphocytes. CD11b is also expressed on microglia in the brain. |
| Applications |
The CD11b antibody can be used to identify and enumerate CD11b+ cells by flow cytometry or fluorescence microscopy.
This antibody is suitable for use in MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. |
| Cross-reactivity |
- Rhesus monkey (Macaca mulatta)
- Cynomolgus monkey (Macaca fascicularis)
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| Clone | Isotype |
| M1/70.15.11.5 | Rat IgG2b |
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| Figure 1 |
| Human PBMCs were stained with CD11b antibodies conjugated to FITC (A), PE (B), or APC (C), and analyzed by flow cytometry. |
| A |
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| B |
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| C |
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| Products |
| CD11b-FITC, human and mouse |
for 100 tests (1)
Download data sheet
130-081-201
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| CD11b-PE, human and mouse |
for 100 tests (1)
Download data sheet
130-091-240
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| CD11b-APC, human and mouse |
for 100 tests (1)
Download data sheet
130-091-241
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 ÎĽL. |
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