CD3
Description The CD3 antibody recognizes the human CD3 antigen which is present on mature human T cells, thymocytes, and a subset of NK cells. CD3 is associated with the T cell receptor (TCR) and is responsible for its signal transduction. The CD3 antigen is a complex of five invariable chains: γ, δ, ε, ζ, and η. The CD3 antibody recognizes all T cells, i.e. it reacts with 70–80% of human peripheral blood lymphocytes and with 65–85% of all thymocytes. The epitope recognized by the antibody is located on the ε-chain of the CD3 complex. Applications The CD3 antibody can be used to identify and analyze CD3+ cells by flow cytometry or fluorescence microscopy. This antibody is suitable for use in MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. Clone Isotype BW264/56 Mouse IgG2a		Figure 1 Human peripheral blood lymphocytes were stained with CD3-FITC and analyzed by flow cytometry.