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| Description |
| CD57 MicroBeads were developed for the separation of human CD57-expressing cells. The CD57 antigen, also known as HNK-1 or Leu-7, is an oligosaccharide antigenic moiety bound to surface proteins of certain cell types. CD57 is present on 15–20% of PBMCs1, including subsets of NK cells and T cells. Also, CD57 expression can be found on a variety of neural cell types.1,2 |
| Applications |
| CD57 MicroBeads can be used for positive selection and depletion of CD57+ cells from PBMCs or other single-cell suspensions. |
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| Figure 1 |
| CD57+ cells were isolated from human PBMCs using CD57 MicroBeads, an MS Column, and a MiniMACS™ Separator. Cells were stained with CD57-APC and analyzed by flow cytometry. |
| PBMCs before separation |
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| CD57- cells |
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| CD57+ cells |
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| Details |
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| References |
| 1. Mechtersheimer et al. (1991) Cancer Res. 51: 1300–1307. |
| 2. Ong et al. (2002) J. Biol. Chem. 277: 18182–18190. |
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