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CD3 MicroBeads
Description
CD3 MicroBeads were developed for magnetic isolation of CD3+ cells. CD3 is expressed on all T cells and CD56+ NKT cells, and is associated with the T cell receptor. 70–80% of human peripheral blood lymphocytes and 65–85% of thymocytes are CD3+. The epitope recognized by CD3 MicroBeads is located on the CD3ε chain.
Applications
CD3 MicroBeads are used for the positive selection1,2,3 or depletion4,5,6 of T cells from peripheral blood, bronchial lavage, cell culture, or various tissues such as lymphoid, nasal, and tumor tissue. T cells isolated by MACS® Technology have been used for various studies, e.g., on T cell cytotoxicity, T cell activation1, HIV infectivity2, signal transduction, and surface marker expression. For information on clinical products click here.
Columns
For positive selection: MS, LS, XS, or autoMACS™ Columns. For depletion: LD, CS, D, or autoMACS Columns.
 
Figure 1
Separation of CD3+ cells from PBMCs using CD3 MicroBeads and a MiniMACS™ Separator with an MS Column.
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Products
CD3 MicroBeads, human
for 109 total cells
Download data sheet
130-050-101
Qty:
 

Related products
CD3 Antibodies
MACS® Cell Analysis Reagents
T Cell Activation/Expansion Kit, human (#130-091-441)
CD56 MicroBeads, human (#130-050-401)
CD56 MultiSort Kit, human (#130-055-401)
MACS References
1. Pitti et al. (1998) Nature 396: 699-703.[517]
2. Heath et al. (1995) Nature 377: 740-744.[177]
3. Lorenzen et al. (1999) J. Exp. Med.190: 1049-1058.[882]
4. Heidenreich and Jovin (1996) J. Neurol. 243: 57-62.[441]
5. Klein et al. (1994) J. Exp. Med.180: 1383-1393.[75]
6. Nicoll et al. (2003) Eur. J. Immunol. 33: 1642-1648.[3107]
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