The PIQOR™ Immunology Microarrays have been designed in cooperation with experts in the field from the Charité and the DRFZ (Deutsches Rheumaforschungszentrum, German rheumatism research centre) in Berlin within the scope of the "NGFN network of infection and inflammation". The microarray configuration is primarily focused on the regulation of cell growth and apoptosis of cells from the immune system.
PIQOR Immunology Microarrays include the key genes for immune response, cell death, extracellular matrix, and signal transduction helping to understand the network and the underlying gene regulation of signaling pathways.
PIQOR Immunology Microarrays are available as a convenient microarray kit or within the scope of Microarray Service. Please see the download area for "Further Information". |
| Gene overview |
Human, mouse: 1,076 genes
Genes are spotted in quadruplicates.
Apoptosis, signal transduction, stress
Caspases, MAP kinases, TRAFs, BCL family, HSP70 family, death domain-containing proteins, tyrosine protein kinases, pi3 kinases, etc.
CD antigens
Cell cycle and DNA repair
Cyclins, BRCA family, p53, p73, DNA ligases, etc.
Chemokines
Chemokine receptors
Complement system
Cytokines
Interleukines, TGFα/β, PDGFα/β, TNFα and other members of the TNF family, IFNγ, BMPs, inhibins, TGFβ family, etc.
Cytokine receptors
Interleukin receptors, TNF receptors, etc.
Cytokine signaling and regulation
JAK/STAT, SOCS, IRAK, NFAT, etc.
Extracellular matrix proteins
Collagens, matrix metalloproteases, TIMPs, matrillins, integrins, laminins, thrombospondins, etc.
Inflammation
NFkB metabolism, TOLL receptors, phospholipases A2, prostaglandin receptors, etc.
Six housekeeping genes and six controls
ACTA2, CYPA, GAPDH, HPRT, TUBA, TUBB, herring sperm DNA, salt, four artificial control RNAs
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| Figure 1 |
| PIQOR Immunology Microarray |
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